Just a handful of cells in the embryo are all that's needed to form the outer layer of pumping heart muscle in an adult zebrafish. Researchers at Duke University Medical Center used zebrafish embryos and careful employment of a new technique that allows for up to 90 color labels on different cells to track individual cells and cell lines as the heart formed. The scientists were surprised by how few cells went into making a critical organ structure and they suspect that other organs may form in a similar fashion, said Kenneth Poss, Ph.D., professor in the Duke Department of Cell Biology and Howard Hughes Medical Institute. The study appears online in Nature. "The most surprising aspect of this work is that a very small number of cardiomyocytes (heart muscle cells) in the growing animal can give rise to the thousands of cardiomyocytes that form the wall of the cardiac ventricle, " said Vikas Gupta, lead author, who is in the Duke Medical Scientist Training Program for M.
Experts are proposing a new model of care collaboration to diagnosis, treat and follow patients who present with various emergent cardiovascular conditions which require rapid, resource-intensive care and confer a high risk of mortality, in an article published in Circulation. Specifically, cardiovascular emergencies, such as ST-segment elevation myocardial infarction (STEMI), non-STEMI/unstable angina, out-of-hospital cardiac arrest (OHCA), acute aortic dissection (AAD), abdominal aortic aneurysm (AAA), stroke and acute decompensated heart failure, may benefit from regionalized systems of care. Over the past decade, the Minneapolis Heart Institute® (MHI) at Abbott Northwestern Hospital has implemented regional systems of care for STEMI, OHCA, AAD, non-STEMI and AAA, instituting clinical programs and a supportive network that reflect a burgeoning framework of a regional cardiovascular emergencies system.
1. For Younger Women at Increased Risk for Breast Cancer, Benefits of Mammography Screening Outweigh Harms According to two new studies being published in Annals of Internal Medicine, younger women at increased risk for breast cancer may benefit from biennial mammography screening beginning at age 40. Currently, major organizations with mammography screening guidelines do not have a consensus on whether to routinely screen all women in their 40s. These data have implications for risk-based screening programs. In the first study, researchers evaluated data from 66 published articles and from the Breast Cancer Surveillance Consortium to determine the factors associated with an increased risk for breast cancer in women aged 40 to 49. Of the 13 possible risk factors examined, the data showed that having extremely dense breast tissue and a first-degree relative with breast cancer (parent, sibling, or child) doubled a woman's breast cancer risk.
A report released at the World Heart Federation World Congress of Cardiology in Dubai reveals significant gaps in public awareness regarding the cardiovascular risks of tobacco use and secondhand smoke. The report, entitled "Cardiovascular harms from tobacco use and secondhand smoke", was commissioned by the World Heart Federation and written by the International Tobacco Control Project (ITC Project), in collaboration with the Tobacco Free Initiative at the World Health Organization. According to the report, half of all Chinese smokers and one-third of Indian and Vietnamese smokers are unaware that smoking causes heart disease. Across a wide range of countries, including India, Uruguay, South Korea and Poland, around half of all smokers - and over 70 per cent of all Chinese smokers - do not know that smoking causes stroke.
There are lots of ways to treat a heart attack - CPR, aspirin, clot-busters and more. Now CU medical school researchers have found a new candidate: Intense light. "The study suggests that strong light, or even just daylight, might ease the risk of having a heart attack or suffering damage from one, " says Tobias Eckle, MD, PhD, an associate professor of anesthesiology, cardiology, and cell and developmental biology at the University of Colorado School of Medicine. "For patients, this could mean that daylight exposure inside of the hospital could reduce the damage that is caused by a heart attack." What's the connection between light and a myocardial infarction, known commonly as a heart attack? The answer lies, perhaps surprisingly, in the circadian rhythm, the body's clock that is linked to light and dark.