Use of criteria such as family history of mania and early onset of illness resulted in the diagnosis of 31 percent more cases of bipolar disorder in individuals experiencing a major depressive episode, according to results of a large international study reported this year. Charles L. Bowden, M.D., clinical professor of psychiatry with UT Medicine San Antonio, was the sole North American author of the study described in Archives of General Psychiatry. UT Medicine San Antonio is the faculty practice of the School of Medicine at The University of Texas Health Science Center San Antonio. Conducted in 18 countries and across cultures, the BRIDGE Study enrolled 5, 635 adults with an ongoing major depressive episode. BRIDGE is short for Bipolar Disorders: Improving Diagnosis, Guidance and Education.
Computer analysis of brain scans could help predict how severe the future illness course of a patient with psychosis will be, according to research funded by the Medical Research Council and the Wellcome Trust. The findings could allow doctors to make more accurate decisions about how best to treat patients. Psychosis is a condition that affects people's minds, altering the way they think, feel and behave. It can be accompanied by hallucinations and delusions. The most common forms are part of mental health conditions such as schizophrenia and bipolar disorder, but symptoms of psychosis can also occur in conditions such as Parkinson's disease and alcohol or drug abuse. Many patients recover from psychosis with minimal symptoms, but for others, the psychosis can be persistent and can affect their ability to function well and lead a normal life.
Generic versions of olanzapine tablets ( Zyprexa ) and olanzapine orally disintegrating tablets (Zyprexa Zydus) for the treatment of schizophrenia and bipolar disorder have been approved by the US Food and Drug Administration (FDA). According to the FDA, approximately 1% of Americans are affected by schizophrenia. WHO (World Health Organization) says that about 1% of people worldwide have schizophrenia. Schizophrenia is a long-term (chronic), severe and disabling brain disorder. Patients may hear voices, believe others are controlling their thoughts or reading their minds... for more information on schizophrenia go to What is Schizophrenia?. Bipolar disorder, or manic-depressive illness is also a brain disorder. The patient has unusual shifts in energy, mood and the ability to function - these shifts can last for weeks, and even months.
Your ability to recognize emotional content in faces and texts is linked to your blood pressure, according to a Clemson University researcher. A recently published study by Clemson University psychology professor James A. McCubbin and colleagues has shown that people with higher blood pressure have reduced ability to recognize angry, fearful, sad and happy faces and text passages. "It's like living in a world of email without smiley faces, " McCubbin said. "We put smiley faces in emails to show when we are just kidding. Otherwise some people may misinterpret our humor and get angry." Some people have what McCubbin calls "emotional dampening" that may cause them to respond inappropriately to anger or other emotions in others. "For example, if your work supervisor is angry, you may mistakenly believe that he or she is just kidding, " McCubbin said.
Low levels of a brain protein that regulates gene expression may play a role in the origin of bipolar disorder, a complex and sometimes disabling psychiatric disease. As reported in the latest issue of Bipolar Disorders, the journal of The International Society for Bipolar Disorders, levels of SP4 (specificity protein 4) were lower in two specific regions of the brain in postmortem samples from patients with bipolar disorder. The study suggests that normalization of SP4 levels could be a relevant pharmacological strategy for the treatment of mood disorders. "We found that levels of SP4 protein in the brain's prefrontal cortex and the cerebellum were lower in postmortem samples from patients with bipolar disorder, compared with samples from control subjects who did not have the disease, " said co-senior author Grace Gill, PhD, an associate professor in the department of anatomy and cellular biology at Tufts University School of Medicine and a member of the neuroscience;