In a study of nearly 18, 000 cancer patients, University of Rochester Medical Center researchers found that when blood clots develop - a well-known and serious complication of cancer treatment - 78 percent of the time they occur when a person is out of the hospital, at home or elsewhere, while on chemotherapy. This data is striking because, until now, outpatients had not been systematically studied and previous data gathered on the incidence of blood clots was mostly from hospitalized patients, who tend to be sicker. However, with a shift toward outpatient cancer treatment, future efforts to prevent blood clots should focus on helping patients to avoid complications so they can continue to live fully, by working, raising children, and exercising, during cancer care, said Alok Khorana, M.
A new study by researchers at the University of California, Berkeley, finds that consuming bushmeat had a positive effect on children's nutrition, raising complex questions about the trade-offs between human health and environmental conservation. They further estimated that a loss of access to wildlife as a source of food - either through stricter enforcement of conservation laws or depletion of resources - would lead to a 29 percent jump in the number of children suffering from anemia. Among children in the poorest households, the researchers added, there would be a three-fold increase in the incidence of anemia. Left untreated, anemia in children can impair growth and cognitive development. The findings are to be published the week of Nov. 21 in the journal Proceedings of the National Academy of Sciences.
According to study published in the New England Journal of Medicine, individuals who receive surgery require less blood after the procedure than commonly thought. The study compared two strategies for administering blood transfusions after surgery. The researchers discovered that no adverse effects from postponing transfusing were shown until patients hemoglobin concentration falls below 8 g/dL or they develop signs of anemia. The study was funded by the National Heart and Lung and Blood Institute. NewYork-Presbyterian Hospital/Columbia University Medical Center is 1 of 47 centers taking part in the FOCUS (Transfusion Trigger Trial for Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair) investigation. The study was led by Dr. Jeffrey Carson, Richard C.
People with low levels of iron in the blood have a higher risk of dangerous blood clots, according to research published in the journal Thorax. A study of clotting risk factors in patients with an inherited blood vessel disease suggests that treating iron deficiency might be important for preventing potentially lethal blood clots. Each year, one in every 1, 000 people in the UK is affected by deep vein thrombosis - blood clots that form in the veins. These can cause pain and swelling, but can also be fatal if the clot is dislodged and travels into the blood vessels of the lungs. Although some risk factors for blood clots are recognised, such as major surgery, immobility and cancer, often there is no clear reason for the blood clot. To look for new risk factors for blood clots, scientists at Imperial College London studied patients with hereditary haemorrhagic telangiectasia (HHT).
A study published online in Nature Genetics reveals that scientists at the Washington University School of Medicine in St. Louis have uncovered a critical genetic mutation in some patients with myelodysplastic syndromes, which is are blood cancers that can progress to a fatal form of leukemia. The researchers also established that patients with the mutation are evidently more likely to develop acute leukemia. Even though this finding needs to be confirmed in additional patients, the study could pave the way for genetic tests in the future that can diagnose the disorder more precisely and predict the course of the disease. Researchers discovered the mutation in a gene known as U2AF1, whilst they were sequencing the entire genome of a 65-year old male with myelodysplastic syndrome that had progressed to leukemia.