Researchers at Moffitt Cancer Center have placed new emphasis on gathering data on cancer patient quality of life during both treatment and survivorship. Their focus is on gathering and using that data to develop interventions to improve the quality of life for patients in treatment and for cancer survivors. Much of the quality of life and survivorship research is carried out by researchers in Moffitt's Department of Health Outcomes & Behavior. "Among the several research goals of the Department of Health Outcomes & Behaviors is the evaluation and improvement of quality of life and quality of care, " said department chair Thomas H. Brandon, Ph.D. "We aim to understand and improve a patient's quality of life throughout the disease course by identifying clinical practices and health outcomes that can inform our efforts to improve the quality of cancer care.
Part of an oral presentation at the recent Society of Surgical Oncology's 65th Annual Cancer Symposium in Orlando, revealed that a stratification of age, race and hormone receptor status helps to predict survival in node-negative breast cancer patients. The study, which was a collaboration of researchers from The Cancer Institute of New Jersey (CINJ), UMDNJ-School of Public Health (SPH) and UMDNJ-Robert Wood Johnson Medical School, shows that the current breast cancer staging system in patients whose cancer has not spread to nearby lymph nodes (node-negative) can be improved by using this information, and that it may prove beneficial for clinicians to predict the outcomes for these patients more accurately. The key predictive factor for women's survival rates with local/regional breast cancer is lymph node staging.
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and University of Kentucky have found that breast cancer survivors who have had chemotherapy, radiation or both do not perform as well on some cognitive tests as women who have not had cancer. They published their study in CANCER. "Survivors of breast cancer are living longer, so there is a need to better understand the long-term effects of cancer therapies, such as chemotherapy and radiation, " said study lead author Paul B. Jacobsen, Ph.D., associate center director for Population Sciences. To carry out their study, the researchers recruited 313 women being treated by either chemotherapy or radiotherapy for early stage breast cancer at Moffitt Cancer Center and the University of Kentucky Chandler Medical Center.
Protein May Be Direct Link That Explains Long-Established Risk Factor Between Alcohol And Breast Cancer
A research team this week presented findings that they say may finally explain the link between alcohol consumption and breast cancer. "Cells have different mechanisms to remove toxic substances, such as ethanol, the chemical name for alcohol, that represent a potential risk to them, " explains MarĂ a de Lourdes RodrĂ guez-Fragoso, professor of pharmacology and toxicology at the Universidad Autonoma del Estado de Morelos in Mexico. "Unfortunately, sometimes these mechanisms produce other toxic substances, including some that are associated with the development of different types of cancer ." RodrĂ guez-Fragoso presented her group's work at the annual meeting of the American Society for Biochemistry and Molecular Biology, held in conjunction with the Experimental Biology 2012 conference in San Diego.
Most people go through life setting goals for themselves. But what happens when a life-altering experience makes those goals become unachievable or even unhealthy? A new collaborative study published in Psycho-Oncology by Carsten Wrosch of Concordia University's Department of Psychology and Centre for Research in Human Development and Catherine Sabiston of McGill's Department of Kinesiology and Physical Education and the Health Behaviour and Emotion Lab found that breast cancer survivors who were able to let go of old goals and set new ones showed an improved well-being overall. Once the self-imposed pressure of now unrealistic goals was removed, individuals' quality of life improved, as did their level of physical activity. Wrosch and Sabiston were interested in looking at how to encourage breast cancer survivors to become more active.