To Slow Rates Of HIV And HPV Transmission In South Africa, Earlier Circumcision In Males May Be Effective Intervention
According to Anna R. Giuliano, Ph.D., program leader in cancer epidemiology at Moffitt Cancer Center in Tampa, Fla., and colleagues in the Netherlands, earlier circumcision of males in South Africa may be a positive step in slowing the spread of both HIV and the human papillomavirus (HPV). Their commentary and data were published in a recent issue of the British medical journal The Lancet Infectious Diseases (Vol. 11) 581-582. "Countries with high incidences of HIV also have high incidences of cancer-related HPV, " said Giuliano. "This is especially true in South Africa." Commenting on a study related to circumcision and HIV and HPV transmission, Giuliano and her colleagues note that studies have shown that circumcision of HIV-infected men does not reduce HPV transmission to their female partners.
Women with cancer-causing strains of human papillomavirus (HPV) may be at increased risk for cardiovascular disease (CVD) and stroke even when no conventional risk factors for CVD are present. Researchers at the University of Texas Medical Branch (UTMB) at Galveston are the first to investigate a potential connection between CVD and HPV, one of the most common sexually transmitted infections in the U.S. Their findings are published in the November 1st issue of the Journal of the American College of Cardiology. "Nearly 20 percent of individuals with CVD do not show any risk factors, indicating that other 'nontraditional' causes may be involved in the development of the disease. HPV appears to be one such factor among women, " said lead author Dr. Ken Fujise, Director, Division of Cardiology at UTMB.
Women infected with cancer-causing strains of the human papillomavirus (HPV) appear also to be at increased for cardiovascular diseases and stroke, even in the absence of other more conventional risk factors, according to new research published in the 1 November issue of the Journal of the American College of Cardiology. Lead author Dr Ken Fujise, Director, Division of Cardiology at University of Texas Medical Branch (UTMB) at Galveston, told the press that nearly 20% of people who develop cardiovascular disease show none of the traditional risk factors normally associated with it, suggesting there are some "non-traditional" risk factors. "HPV appears to be one such factor among women, " he suggests. "This has important clinical implications. First, the HPV vaccine may also help prevent heart disease.
The CDC's ACIP (Advisory Committee on Immunization Practices) has recommended the routine administration of 3-doses of HPV4 vaccine to protect against HPV (Human Papilloma Virus). The Committee said the vaccine will not only protect males from some HPV-related conditions, such as genital warts and oral, penile and anal cancers, but will also indirectly protect females by reducing HPV infection risk, a common cause of cervical cancer. A significant proportion of cervical cancers result from vaginal sex with HPV infected males. Private health insurers usually cover the costs of vaccines recommended by ACIP for routine use. The HPV vaccine, at over $300 for the three doses, is particularly expensive. Families in the USA often pay over that amount when pediatricians present them with their bill.
The CDC has added still another vaccine to the recommended list: three doses of human papillomavirus (HPV) vaccine ( Gardasil ) for boys age 11-12. HPV causes genital warts, and four of about 100 strains have been linked to cancer, especially cervical cancer in women. Controversy over Governor Rick Perry's effort to mandate the vaccine for sixth-grade girls spilled into the Presidential campaign when he was criticized by Michele Bachmann. The CDC's decision was praised by Dr. Gilbert Ross of the American Council on Science and Health, who said that "gender parity is necessary here." Men transmit the virus to women and can get anal cancer from it. The recommendation "also serves to equalize the burden of vaccination to not just one gender, " stated Dr. Joel Palefsky of the Anal Neoplasia Clinic at the University of California at San Francisco.