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[ Probing How Chronic Alcoholism Alters Cellular Signaling Of Heart Muscle ]

Probing How Chronic Alcoholism Alters Cellular Signaling Of Heart Muscle

Beyond the personal tragedy of chronic alcoholism there is heartbreak in the biological sense, too. Scientists know severe alcoholism stresses the heart and that mitochondria, the cellular energy factories, are especially vulnerable to dysfunction. But they don't know the precise mechanism. Now new experiments led by a team at the Wadsworth Center of the New York State Department of Health in Albany, and Thomas Jefferson University in Philadelphia, may provide insights into possible modes of heart damage from alcohol. The teams will present their findings at the 56th Annual Meeting of the Biophysical Society (BPS), held Feb. 25-29 in San Diego, Calif. Using a technique called electron microscopic tomography, the Albany group produced the first 3D images of mitochondria and discovered tiny tethers linking mitochondria to another cell compartment, the endoplasmic reticulum (ER), where calcium is stored.

Best Practices In Implementing Green Pharmaceutical Manufacturing Conference, 13-14 November 2012, Vienna

This unique and timely event will highlight how different frameworks and initiatives have succeeded in developing an efficient environmentally friendly manufacturing process in the pharmaceutical industry. Case studies will be presented to focus on the challenges faced by manufacturers, but through real experiences we will review examples of successful implementation that ultimately lead to cost effective rewards. Why attend? Hear experiences from the leaders in sustainable manufacturing and learn how to implement green strategies from organisations who have successfully applied green manufacturing initiatives. Comprehend the various planning strategies available for your manufacturing site. Benchmark your strategies in implementation, restructuring and up-scaling the manufacturing plant.

Pharmaceutical And Medical Device Market Access In Key Asian Markets Conference, 23-24 May 2012, Singapore

Reacting to new developments to optimize pricing and marketing approaches for fast-growing and complex Eastern markets Asian markets are increasingly the focus of pharmaceutical companies who are looking for new market opportunities beyond the traditional "rich-world" countries who are facing economic stagnation. Traditionally, more "mature" and higher income Asian markets such as Japan, Korea, Taiwan, Singapore and Hong Kong have been seen as the priority of pharma marketers, but now fast-developing, high-population countries such as China, India, Indonesia, Vietnam and Thailand, are increasingly the priority. Altogether, these developed and developing Asian countries cover around half of the world's population and are increasingly dominating pharmaceutical sales growth. This event will bring together experts responsible for key Asian markets globally and locally to discuss how the current changing environments will impact on market access in these markets and as a result affect global strategies.

World Immunology Online Conference Held On March 15-17, 2012: All Presentations And Discussions In Real Time

Target Meeting is a leading life science conference organizer. They specialize in organizing conferences, symposiums and workshops, which brings together the known researchers, professors and life science suppliers from across the world to debate over the latest developments in biomedical research. The 2012 World Immunology Online Conference scheduled to be held on March 15 - 17, 2012. The 10 sessions, which will be spread over three days will discuss immune regulation and pathway, cancer and immunity, immunotherapy, stem cells and immunity, infection and immunity, immunity disease and clinical, immunity diseases molecular mechanisms, and many more. 50 leading professors and researchers will give oral presentations at the online conference. Conference speakers include: Choun-Ki Joo, Professor, Director, The Catholic University of Korea, Korea.

Open Innovation In Pharmaceutical R D Conference, 26-27 April 2012, Amsterdam

With most blockbuster drugs going off-patent and not enough new drugs entering the market to compensate, the pharmaceutical industry is under pressure for more innovation. With this being said, it is now the perfect time to gather the leading pharmaceutical experts to discuss the new R&D projects such as alliances and agreements with academic or biotech research teams that seem to serve as a very effective response to this challenge. Fleming Europe's Open Innovation in Pharmaceutical R&D on 26 - 27 April 2012 in Amsterdam will address these issues from the view of all the major stakeholders. Representing small biotech firms, Beatrice De Vos, Chief medical officer of Promethera Biosciences, will speak about Dynamics of big pharma, SME, and academic research in pharmaceutical R&D. Among others, the question of the use of open innovation in the current legal, regulatory, and commercial environment will be answered.

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