People who have experienced a stroke or transient ischemic attack (TIA) experience high rates of depression, but up to two-thirds of them are undertreated, according to new findings from Duke University Medical Center. Daniel Laskowitz, M.D., a professor of medicine at Duke and the senior author of the study published in the American Heart Association journal Stroke, called the findings "striking." Because depression was just as common in TIA, which typically does not result in disabilities as a stroke can, "the findings suggest this is not just a simple association between depression and the functional impairment typically associated with stroke, " Laskowitz said. Rather, several factors may be responsible. The brain injury associated with stroke and TIA might cause the depression, or the vascular risk factors that predispose patients to stroke and TIA may also put them at risk for depression.
Obstructive sleep apnea and other symptoms of OSA are associated with probable major depression, regardless of factors like weight, age, sex or race, according to a new study from the Centers for Disease Control and Prevention. There was no link between depression and snoring. "Snorting, gasping or stopping breathing while asleep was associated with nearly all depression symptoms, including feeling hopeless and feeling like a failure, " said Anne G. Wheaton, PhD, lead author of the study. "We expected persons with sleep-disordered breathing to report trouble sleeping or sleeping too much, or feeling tired and having little energy, but not the other symptoms." The study, appearing in the April issue of the journal SLEEP, is the first nationally representative sampling to examine this relationship, surveying 9, 714 American adults.
A study presented at the 12th Annual Spring Meeting on Cardiovascular Nursing In Copenhagen, Denmark, has demonstrated that the risk of mortality increases in patients with a coronary stent implant. At the 7-year follow up, depressed stent-implant patients, regardless of age, gender, clinical characteristics, anxiety and distressed (Type D) personality, were one-and-a-half times more likely to have died from depression, compared with patients who did not suffer from depression. Even though depression has been linked to poor outcomes in coronary artery disease, earlier studies predominantly investigated the short-term effects, mainly in patients who suffered a myocardial infarction or underwent coronary bypass operation. In this new study, the researchers decided to examine what effect depression might have on mortality in patients who underwent percutaneous coronary intervention (PCI) during a 7-year follow up period.
Depression increases the risk of death in patients who have a coronary stent implanted. After seven years of follow up, depressed patients were 1.5 times more likely to have died than non-depressed patients. The findings were independent of age, gender, clinical characteristics, anxiety and the distressed (Type D) personality. The research was presented at the 12th Annual Spring Meeting on Cardiovascular Nursing, in Copenhagen, Denmark. Depression has been associated with poor outcomes in coronary artery disease but previous studies have mainly looked at short term effects, primarily in patients who have had a myocardial infarction or a coronary bypass operation. The current study (FPN 17) investigated the impact of depression on mortality during a 7-year follow up period in patients treated with percutaneous coronary intervention (PCI).
Electroconvulsive therapy (ECT) works by altering how different parts of the brain involved in depression communicate with each other, Scottish researchers reported in the journal PNAS (Proceeding of the National Academy of Sciences). ECT has been an effective and controversial therapy for depression for over seven decades; doctors knew it would often work, but were never sure why. For individuals with serious mood disorder, using ECT, which involves anesthetizing them and using an electric shock to induce a seizure, has been the most effective treatment available for a long time. A team of doctors and scientists from the University of Aberdeen and the University of Dundee, both in Scotland, have demonstrated that ECT impacts on how parts of the brain communicate - parts involved in depression.