A study of nearly 4, 000 teenagers published online in the Journal of Epidemiology and Community Health, shows that secondary school children who take methamphetamine (speed) and MDMA (ecstasy) appear to be prone to depression later on. The study results proved to be independent of previous bouts of depressive symptoms or other drug use. Speed and ecstasy first gained popularity amongst clubbers and people in the rave scene. However, both drugs have also become increasingly popular in the general population, such as secondary school children, who, according to the researchers, often take both drugs at the same time. Because of increasing concerns that these synthetic drugs could cause long-term neurological damage, particularly in those where the brain is still being developed as in adolescence, ‚ ®the researchers decided to conduct a study ‚ ®by tracking the mental health of a sample of 3, 880 secondary school children of disadvantaged areas in Quebec, Canada between 2003 and 2008.
Princeton University researchers have observed a self-degradation response to the antidepressant Zoloft in yeast cells that could help provide new answers to lingering questions among scientists about how antidepressants work, as well as support the idea that depression is not solely linked to the neurotransmitter serotonin. In findings published in the journal PLoS ONE, researchers based in the lab of Ethan Perlstein, an associate research scholar in Princeton's Lewis-Sigler Institute for Integrative Genomics and lecturer in molecular biology, report that sertraline - trademarked as Zoloft - accumulated in the internal membranes of baker's yeast cells. This buildup caused a swelling and sharp curvature in the membranes of vesicles, bubble-like cell components with a hand in cell metabolism, movement and energy storage.
Over the last few decades numerous studies have shown negative states, such as depression, anger, anxiety, and hostility, to be detrimental to cardiovascular health. Less is known about how positive psychological characteristics are related to heart health. In the first and largest systematic review on this topic to date, Harvard School of Public Health (HSPH) researchers found that positive psychological well-being appears to reduce the risk of heart attacks, strokes and other cardiovascular events. The study was published online in Psychological Bulletin. The American Heart Association reports more than 2, 200 Americans die of cardiovascular disease (CVD) each day, an average of one death every 39 seconds. Stroke accounts for about one of every 18 U.S. deaths. "The absence of the negative is not the same thing as the presence of the positive.
While mood disorders like depression or anxiety tend to negatively affect treatment for allergies and chronic rhinosinusitis, the same cannot be said for patients with nasal obstructions such as deviated septum, according to researchers at Henry Ford Hospital. The new study shows mood disorders are not linked to either nasal obstructive symptoms or the failure of nasal obstruction surgery. Results also suggest that those patients with nasal obstruction caused by septal deviation - a blockage of the nasal airway caused by a portion of cartilage or bony septum - who do not have signs and symptoms of allergic rhinitis would not benefit from depression screening if nasal treatment is unsuccessful. "Although the literature supports more negative outcomes of allergic rhinitis and chronic rhinosinusitis patients with mood disorders, our data does not show a similar relationship for septal deviation, " says study author Lamont R.
Depression may be associated with an increased risk of arterial narrowing in the legs and pelvis, a condition known as peripheral artery disease (PAD), according to research presented at the American Heart Association's Arteriosclerosis, Thrombosis and Vascular Biology 2012 Scientific Sessions in Chicago. While experts know that depression is a risk factor for constricted heart arteries, its effect on PAD is uncertain. Researchers used data from 1, 024 men and women in the Heart and Soul Study and followed them for about seven years. At the study's start, 12 percent of participants with depression had PAD, compared to seven percent of patients without depression who had PAD. Similarly, nine percent of depressed patients and six percent of those without depression had PAD-related events during the seven-year follow-up.