A study published in BMJ (British Medical Journal) states that there are no long term benefits from type 2 diabetes group education programs that only take place once. Type 2 diabetes, a chronic disease which can lead to amputation, loss of vision, kidney failure and many other health problems, requires a person to be extremely vigilant in caring for themselves when it comes to medication, treatment and caring for their symptoms. The UK's Diabetes National Service Framework and the National Institute for Health and Clinical Excellence (NICE) both support and recommend education programs to diabetics, starting at the time they are diagnosed. Former studies have shown that the Diabetes Education and Self Management for Ongoing and Newly Diagnosed, or DESMOND, was successful in giving patients a positive outlook and that patients' feelings about their disease were improved.
Type1 diabetes is caused by autoimmune destruction of the insulin-producing beta cells. Over 250, 000 patients suffer from type 1 diabetes in Germany who are treated with daily insulin injections to maintain glucose metabolism. Replacement of the destroyed beta cells by transplantation of either a complete pancreas organ or isolated human beta cells is the only effective way to cure the disease. However, due to the shortage of organ donors this method can be offered to only few patients. As an alternative approach researchers are exploring xenotransplantation, i.e. transplantation of the organ from another species. The most obvious barrier in xenotransplantation is the strong immune rejection against the transplant. A research team led by LMU's Professor Eckhard Wolf and Professor Jochen Seissler has now generated a genetically modified strain of pigs whose beta-cells restores glucose homeostasis and inhibit human-anti-pig immune reaction.
Takeda says it has received a complete response letter from the FDA regarding NDAs (new drug applications) for alogliptin and fixed-dose combination alogliptin and pioglitazone - both diabetes type 2 investigational therapies. Takeda says it has recently been providing the FDA (Food and Drug Administration) with postmarketing data from markets outside the USA. Takeda believes it can provide the additional information from postmarketing data from non-USA markets, as well as findings from its current clinical trial program. Thomas Harris, vice president, regulatory affairs, Takeda Global Research & Development Center, Inc., said: "We will immediately request a meeting with the FDA to determine the appropriate next steps and are committed to addressing outstanding issues. We remain confident in the benefit that alogliptin will bring to patients with type 2 diabetes in the U.
Fighting Harmful Free Radicals Tied To Aging And Cancer With Avocado Oil: The 'Olive Oil Of The Americas'?
Atmospheric oxygen facilitated the evolution and complexity of terrestrial organisms, including human beings, because it allowed nutrients to be used more efficiently by those organisms, which in turn were able to generate more energy. However, as we find out more about how oxygen molecules work inside the body, more attention is being paid to their not-so-good effects, and researchers are seeking ways to thwart them. A number of environmental factors - such as pollution, cigarette smoke and radiation - can turn the oxygen molecules found in mitochondria, the power plants of cells, into free radicals. These unstable molecules destroy virtually all the normal molecules forming cells, such as lipids, proteins and even DNA, by turning them into free radicals, too. This destructive phenomenon is associated with aging and occurs in a variety of diseases, including hypertension and diabetes, which represent major challenges for health systems due to their great social and economic costs.
About 26 million Americans suffer from type 2 diabetes. A study in BMC Complementary and Alternative Medicine has now revealed that complementary and alternative medicine (CAM), in adjunction to conventional medicine, holds various positive benefits for people with type 2 diabetes, compared with those who only receive conventional medicine. For instance, better eating and exercise habits lower blood sugar levels, improve moods and give the person a stronger sense of control over their condition. Ryan Bradley, ND, MPH, director of the Diabetes and Cardiovascular WellnessClinic at Bastyr Center for Natural Health declared: "The news is encouraging for those fighting the disease. Patients involved in the study cited the benefits of trying different approaches to find the best ways to minimize the effects of type 2 diabetes.