Adult males with strong immune systems are seen as more sexually attractive to females, researchers from the University of Abertay Dundee, Scotland, wrote in the journal Nature Communications. They added that a strong immune system plays a greater role in attracting women to men, than great bodies or muscles. There appears to be an association between testosterone levels, facial attractiveness, and cortisol, the authors informed. Cortisol is a stress hormone. The researchers explain that men with healthy immune systems tend to have higher testosterone levels, and it is the healthier immune system that impacts on attractiveness. A man's face is more attractive, usually, if he has high levels of testosterone. However, nobody has fully understood how testosterone affects immune function.
Zebrafish Study Finds A Unique On-Off Switch For Hormone Production Which Likely Exists In The Human Brain
After we sense a threat, our brain center responsible for responding goes into gear, setting off a chain of biochemical reactions leading to the release of cortisol from the adrenal glands. Dr. Gil Levkowitz and his team in the Molecular Cell Biology Department have now revealed a new kind of ON-OFF switch in the brain for regulating the production of a main biochemical signal from the brain that stimulates cortisol release in the body. This finding, which was recently published in Neuron, may be relevant to research into a number of stress-related neurological disorders. This signal is corticotropin releasing hormone (CRH). CRH is manufactured and stored in special neurons in the hypothalamus. Within this small brain region the danger is sensed, the information processed and the orders to go into stress-response mode are sent out.
The U.S. Food and Drug Administration has approved Korlym (mifepristone) to control hyperglycemia (high blood sugar levels) in adults with endogenous Cushing's syndrome, who have type 2 diabetes or glucose intolerance, who remained unresponsive to previous surgery or are not eligible candidates for surgery. Pregnant women should never take Korlym (contraindicated). Until the FDA approved Korlym for the treatment of endogenous Cushing's syndrome, there were no approved medications to treat the disorder. Endogenous Cushing's syndrome is a debilitating and rare multisystem disorder which affects individuals mainly between the ages of 25 and 40. The disorder is caused by excess levels of the hormone cortisol. Cortisol is a steroid hormone produced by the adrenal glands that increases blood sugar levels.
Flexible Duration Of Hormone Therapy Use For Many Women Endorsed By The North American Menopause Society
A great deal has been learned in the ten years since the first results emerged from the Women's Health Initiative (WHI). Hormone therapy (HT) remains the most effective treatment available for menopausal hot flashes and night sweats. However, there is a growing body of evidence that formulation, route of administration, timing of therapy and duration of therapy may produce different effects. It is essential to evaluate a personal benefit-risk profile for each woman considering HT. Individual factors contributing to the HT decision include the severity of menopausal symptoms and effect on quality of life. The absolute risks of HT in healthy women ages 50 to 59 are low. In contrast, long-term HT or HT initiation in older women is associated with greater risks. SUMMARY The recommendation for duration of therapy differs for Estrogen Progestogen Therapy (EPT) in women with a uterus, and Estrogen Therapy (ET) in women who have had a hysterectomy.
Two independent groups of researchers - one led by Adrian Clark, at Queen Mary University of London, United Kingdom; and the other led by Jean-Laurent Casanova, at The Rockefeller University, New York - have now identified the disease-causing gene in patients with a complex inherited syndrome most commonly observed in the Irish Traveller community. As noted by Jordan Orange, at the University of Pennsylvania School of Medicine, Philadelphia, in an accompanying commentary, the new data provide deep mechanistic insight into a complex human condition and expand our understanding of the human immune and endocrine systems, both of which are disrupted in patients. Within the Irish Traveller community, several families have been found to suffer from an inherited condition characterized by failure of the adrenal glands to produce adequate amounts of steroid hormones, abnormal development (in particular, retarded growth), and a deficiency in immune cells known as NK cells.