Tadalafil, known under the brand name Cialis for the treatment of erectile dysfunction and Adcirca for pulmonary arterial hypertension, is a PDE5 inhibitor. Its main competitors are sildenafil citrate ( Viagra ) and vardenafil ( Levitra ). Tadalafil's chemical formula is C 22 H 19 N 3 O 4. Cialis became nicknamed "the weekend pill" because its effects last 36 hours. Viagra and Levitra are effective for up to 8 hours. A PDE5 (phosphodiesterase type 5) inhibitor is a medication used to block the degradative action of cyclic GMP (cGMP) in the smooth muscle cells that line the blood vessels that supply the corpus cavernosa (two tubes that run the length of the penis). PDE5 is also present in the smooth muscle of the walls of the arteries within the lungs - hence, it has also been explored for pulmonary hypertension treatment.
Teaching males to control their minds and bodies so that they can overcome a premature ejaculation problem during sex does not appear to be backed by reliable evidence, researchers revealed in a Review published in The Cochrane Collaboration. Two authors, however, added that so-called behavioral therapy should not be discounted yet, before further studies are done. Stanley Althof, executive director of the Center for Marital and Sexual Health of South Florida, said: "We need to do more to prove it works." Experts define premature ejaculation as ejaculation that occurs within a minute of placing the penis inside the vagina. Nobody is sure what percentage of men experience premature ejaculation, and how often. Althof says that approximately between 2% to 5% of men suffer from premature ejaculation if the one-minute definition is used strictly.
Researchers have found a potential new source for sexual problems among middle-aged and older men: The relationships between their female partners and the men's closest friends. Cornell University and University of Chicago researchers have found a connection between erectile dysfunction and the social networks shared by heterosexual men and their partners. The researchers describe the situation as "partner betweenness." In such cases, a man's female partner has stronger relationships with his confidants than the man does - in effect, the romantic partner comes between the man and his friends. "Men who experience partner betweenness in their joint relationships are more likely to have trouble getting or maintaining an erection and are also more likely to experience difficulty achieving orgasm during sex, " write Benjamin Cornwell, Cornell professor of sociology and Edward Laumann, University of Chicago professor of sociology in the paper.
Viagra is the brand name for Sildenafil citrate, and is used for treating erectile dysfunction and pulmonary arterial hypertension. Originally developed by scientists in Great Britain, it was brought onto the market by Pfizer Inc., a US pharmaceutical company. Viagra is also sold under brand name Revatio. Sildenafil citrate's chemical formula is C 22 H 30 N 6 O 4 S. Viagra works by inhibiting an enzyme called cGMP-specific phosphodiesterase type 5, that delays degradation of cGMP, which controls blood flow in the penis. It came onto the market in 1998 and has become the prime treatment for impotence (erectile dysfunction). Viagra's main competitors are Cialis (tadalafil) and Levitra (vardenafil). Dosage Viagra, for erectile dysfunction, comes in blue, diamond-shaped pills, in doses of 25, 50, or 100 milligrams.
Erectile dysfunction, also known as ED or impotence, is a male's inability to achieve or maintain an erection that is sufficient for sexual intercourse. Occasional erection problems are not necessarily something to worry about. However, if the problem is ongoing, it may cause anxiety, stress, undermine self-confidence, and affect some relationships. A significant proportion of men with erectile problems are embarrassed to talk to their doctor about it. However, individuals should go in for an evaluation. Not only because the condition can often be effectively treated, but also because erectile dysfunction may be a sign of an underlying health problem, such as diabetes, high blood pressure, or a cardiovascular disease, some of which may be life-threatening. Treating an underlying health problem may also cure the erectile dysfunction.