A group of scientists from Mayo Clinic have set off for Mount Everest in Nepal to study the performance of nine climbers as they attempt to reach the summit of the world's highest mountain. The athletes will be monitored from the time they leave base camp at 17, 500ft above sea level, up to the summit at 29, 000 feet and back down again. The climbers will take two different routes. The purpose of the study is to better aid physiologists in understanding the stresses the body goes through during extreme endurance, such as mountain climbing. It is hoped that the research will aid with treating heart patients. The mountain's altitude makes it the perfect natural laboratory for the study of heart disease, lung problems, muscle loss, sleeping disorders, as well as new medical technologies.
Having a virtual copy of a patient's blood in a computer would be a boon to researchers and doctors. They could examine a simulated heart attack caused by blood clotting in a diseased coronary artery and see if a drug like aspirin would be effective in reducing the size of such a clot. Now, a team of biomedical engineers and hematologists at the University of Pennsylvania has made large-scale, patient-specific simulations of blood function under the flow conditions found in blood vessels, using robots to run hundreds of tests on human platelets responding to combinations of activating agents that cause clotting. Their work was published in the journal Blood. Patient-specific information on how platelets form blood clots can be a vital part of care. Normally, clots prevent bleeding, but they can also cause heart attacks when they form in plaque-laden coronary arteries.
3 new studies from India, China and Middle East expose the extent of the problem in new data presented at the World Congress of Cardiology. Women with acute coronary syndrome - (ACS) receive inferior or less aggressive treatment compared to men, according to three large studies presented at the World Congress of Cardiology. The CREATE registry study of 20, 468 patients in India revealed that relatively fewer women are admitted with ACS. Moreover, these women are older, reach hospital later, have more risk factors, receive inferior treatments and have worse outcomes. While the BRIG project study of 3, 168 patients in China concluded that a substantial portion of women with ACS did not receive proper treatment during hospitalization compared with men. Similarly, a study of 4, 229 ACS patients in the Middle East found that women tended to be admitted to hospital later than men and had more comorbid disease.
High normal blood pressure becomes less of a risk factor for incident cardiovascular disease (CVD) and coronary heart disease (CHD) with age, according to a new study presented today at the World Congress of Cardiology. The study, carried out over 9.3 years, evaluated the risk of different blood pressure categories among 6, 273 participants aged 30 years old and above. The results showed that the risk of developing incident CVD and CHD was significantly higher in people with high normal blood pressure during middle-age (between 30 and 60 years of age) than for people with the same high normal blood pressure aged 60 years and older. Incident CVD and CHD risk was, however, similarly high in people with diagnosed high blood pressure across all age-groups. "These results reinforce the fact that high blood pressure is a serious risk for CVD in all age groups, " said Dr.
Rheumatic heart disease (RHD) is significantly under-treated in Africa and India according to the preliminary findings of a new global study presented at the World Congress of Cardiology. Across the African and Indian regions included in the study it was revealed that patients are not receiving the surgery they need, secondary prevention with penicillin - to prevent further attacks of rheumatic fever - is being under-utilized and many patients are unaware of their target anti-coagulation levels. Specifically, only 41 per cent of patients enrolled in the study had received surgery. As the pilot results included a large tertiary academic centre, this does not reflect the dire lack of surgery available at the majority of enrolling centers. In fact, more than 85 per cent of the enrolling centres do not have surgery available on a regular basis for RHD patients.